The guideline population was defined to be people who are receiving a blood transfusion or are at risk of receiving a blood transfusion for some review questions alternatives to blood transfusion the review population was limited to surgical patients who are receiving blood transfusions. Whole blood transfusion cpg id 21 guideline only not a substitute for clinical judgment 3 background the first documented animal to animal dog blood transfusion was performed at oxford in 1665 by richard lower followed by the first animal to human blood transfusion in 1667 by jean denis the first human to. Some conditions require more than one blood transfusion clinical trials explore mayo clinic studies testing new treatments interventions and tests as a means to prevent detect treat or manage this disease the mayo clinic experience and patient stories. Principles of clinical transfusion practices avoid blood transfusion transfusion is only one part of the patients management prevention and early diagnosis and treatment of anemia underlying condition use of alternative to transfusion eg iv fluids good anesthetic and surgical management to minimized blood loss. Therefore clinical situations where blood transfusion is beneficial to the patient and improves outcome are limited the decision to administer blood should be taken after weighing the risks and benefits of blood transfusion against those of anaemia a brief summary of indications of blood transfusion is given in table 1
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